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NATIONAL SCIENTIFIC CENTER
OF PHTHISIOPULMONOLOGY
Ministry of health of the Republic of Kazakhstan
Report About the visit of laboratory specialists to Korea for study molecular genetic diagnosis of XDR-TB
1. This visit was made in South Korea by laboratory specialists of TB dispensaries. The visit was attended by 5 specialists from 20.08 2018 to 25.08.2018:
  • Toksanbaeva B.T. - Head of National reference bacteriological laboratory (NRBL) of NSCP RK
  • Chingisova L.T. - doctor bacteriologist of National reference bacteriological laboratory of NSCP RK, Ph.D.
  • Zhazykbaeva Zh.- head of the bacteriology laboratory of Zhambyl region’s TB Dispensary
  • Omarova N. - head of the bacteriology laboratory of the Almaty City’s TB Dispensary
  • Kurmasheva A. - doctor bacteriologist of Talgar TB Dispensary, Almaty region.
2. The purpose of the visit is to conduct studies on the new molecular genetic equipment Exipower (Bioneer) to determine the drug resistance to drugs in the reserve series. The training was conducted by two country’s specialists: from Kazakhstan and Azerbaijan.
 
3. Exipower device was first delivered to NRBL of NSCP RK at 2016. There was carried out validation of the drug resistance testing method for the drugs of the main series (isoniazid and rifampicin) within a year (2016-2017). At 2017-2018 was carried out the study of drugs of the reserve series (fluoroquinolones, injection TB drugs). In the second quarter of 2018, five vehicles were delivered to Almaty, Talgar, Zhambyl, Kostanai, and Atyrau regions additionally.
 
4. At 20.08.2018 a visit carried out to the advanced laboratory of international level "GCLabs", which contains all molecular genetic studies of South Korea, including Exipower device. The main purpose of this laboratory is the study of no communicable diseases.
 
5 The training was conducted on the Exipower device at the training center of the corporation Bioneer (Daejeon city) from 21.08.18 to 24.01.2018.
 
6. On the first day, testing was conducted for our specialists, during which we successfully demonstrated practical skills in molecular genetic rapid diagnosis of TB and MDR-TB.
 
7. After that, the teachers of the training center conducted training on the development of theoretical knowledge and practical skills in the rapid diagnosis of XDR TB.
 
8. The molecular-genetic device Exipower makes it possible to determine resistance to fluoroquinolone and injections, as well as to streptomycin and ethambutol.
 
9. All specialists received certificates upon completion of training.
 
10. A meeting was held on August 24, 2018 with the president of Bioneer Corporation Han-Oh Park, PhD and the representative of the international research center (International Tuberculosis Research Center) Jongseok Lee, PhD, during which the research was discussed at Exipower. The president provided information that TB reagents had successfully completed study in the FIND, they were advised to add a further study of kanamycin at low concentrations, as in the latest LPA (HAIN) kit. In addition, all diagnostic kits for TB and M / XDR TB on Exipower are transferred to a study at the International Tuberculosis Research Center in Korea.
 
11. International Tuberculosis Research Center is researching new sets, before this center also conducted research on Xpert and Ultra cartridges.
 
12. There were discussed during the meeting the issues of joint research and publications with the International Tuberculosis Research Center.
 
13. This visit of specialists was conducted to South Korea with the support of the organization LLP LifeMedHolding.
 
 
 

 

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